We excluded studies published in a language other than English, French, Spanish or Mandarin. Two reviewers screened each citation. Trials that were considered to be relevant by any reviewer were retrieved, and the full text was independently assessed by 2 reviewers for inclusion. Disagreements were resolved ENMIC 6LB a third party through consensus. We assessed the quality of the studies using characteristics from the Chalmers index 9 as well as other characteristics that may affect the risk of bias. Viewsonic[…]