Gabe at Macdrifter wrote about his Pause TimeMachine Macro which he uses when he starts using Skype. He adds that he knows there are other (potentially "better") to do this, but that his was just a fast and dirty solution.
Seeing Gabe's macros reminded me that I have wanted something like this for when I am recording the Impolite Company podcast. Gabe's macro enables and disables Time Machine, but I also want to enable and disable CrashPlan and Dropbox. Like Gabe