Here's a list of all the proprietary stuff Apple has shoehorned into the "best Mac it has ever made", the MacBook Pro with Retina display (henceforth referred to as "MBPwRD"), taken from the iFixit teardown:
Irritating pentalobe screws, which don't stop anyone determined to disassemble their MBPwRD but mean you need to waste time buying special drivers on eBay.
RAM soldered to the motherboard, as we all suspected. No ability to upgrade it after purchase. I couldn't find anywhere on apple.com that makes this limitation clear to shoppers, either. That strikes me as disingenuous.