Macoscope has released version 2.0 of its XCode navigation plugin, Code Pilot. Technically it's still a beta -- judging from the 2.0b6 version number -- but it's been rock solid for me so far. This version brings XCode 4 compatibility and a revamped interface. If you code and you haven't tried it, definitely take a look.
Code Pilot attaches to Shift-Command-X in XCode, and the hotkey brings up a HUD with a search field focused. As you type, it quickly and intelligently filters the files in your project down to the one you were looking for. It also searches symbol names across the board or within the selected file (add a space after the filename). It's similar to XCode's Open Quickl