Great news for y'all out there trying to get your flicks onto your iPod. Open Source Handbrake now accepts just about any type of file for input. That means DIVX AVI's, WMF's and ASF files are all fair game for iPod users. Ironically, for legal reasons, you can no longer natively encode DVD's (the previous main reason for Handbrake). You'll need the assistance of VLC, which any self respecting Mac video user already has on their machine.
See it in action below. Note that it is a speed burner on the new Unibody MacBooks operating at about the same speed as Quicktime Pro - which it largely renders irrelevant. It also has some great batch conversion functionality which can convert "whole seasons" of AV