Scientists have developed a new implantable device that has the potential to change the way Type 1 diabetics receive insulin. The thread-like implant, or SHEATH (Subcutaneous Host-Enabled Alginate THread), is installed in a two-step process that ultimately leads to the deployment of “islet devices,” which are derived from the cells that produce insulin in our bodies naturally.
First, the scientists figured out a way to insert nylon catheters under the skin, where they remain for up to six weeks. After insertion, blood vessels form around the catheters which structurally support the islet devices that are placed in the space when the catheter gets removed. The newly implanted 10-centimeter-long islet devices secrete insulin via islet cells that form around it, while also receiving nutrients and oxygen from blood vessels to stay alive.
The implantation technique was designed and tested by researchers at Cornell and the University of Alberta. Cornell’s Minglin Ma, a Professor of Biological and
