The spray is used daily, approximately 30 minutes before going to bed. It works by increasing the absorption of water through the kidneys, which leads to less Chronos ESS Solo production. The product was approved with a boxed warning and a medication guide because it can cause hyponatremia. It should not be used in patients at increased risk of severe hyponatremia or in patients with symptomatic congestive heart failure or uncontrolled hypertension. The product, a generic version of Pristiq Pfizeris[…]